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American Society Cell Biology, Moscone Center, San Francisco, CA - Dec 2005

Applied Precision is the leading company in the field with 3D-Structured Illumination microscopy with currently 20 installed OMX systems worldwide.

At the ASCB 2010 Meeting in December 2011 they have launched 3 new models at a much lower price than the first OMX versions.

These new models include:

OMX V4™ SI , the new entry level System with 3D-Structured Illumination, multiple color (filter wheel), single camera system

· X,Y resolution between 80-120 nm

· Z resolution between 250-350 nm (depending on wavelength)

· Improved rotary stage

· ~5 sec for 2 um, 512x512 (exp dependant)

· 1 camera with 1 filter wheel

· 405, 488, 561 lasers standard

· 60x 1.42 NA objective

OMX V4 Monet™ ,

· Localization Microscopy

· New advanced TIRF design

· 20-50 nm resolution using Monet™ Localization Software

– Proprietary Mixed Model Algorithm for fluorophore localization

– Fewer acquisition scans needed

– Can work with photoswitchable (PALM) or photoactivatable (STORM) localization systems

OMX V4 Dual mode

· 3D-SIM

· Monet™ Localization Microscopy

· 2 camera, 2 Filter Wheels

· 4 lasers Standard

– 405 nm

– 488 nm

– 561 nm

– 642 nm

OMX V4 Blaze

· New light pattern generation technology (patent pending)

· Fast 2D/3D SIM Imaging

· <1 sec per stack

· >20 fps 2D-SIM

· Ultra fast widefield imaging (>100 fps)

· New optical block design

· 5 lasers, 405, 440, 488, 514, 561

· 3 CMOS cameras standard

Configuration	DeltaVision OMX®	OMX V4 SI	OMX Blaze
Standard Camera/Filter Setup	2 cameras, filter drawers	1 camera + Filter wheel	3 cameras + Filter drawers
Additional Cameras*	Optional, 4 max	Optional, 4 max	Optional, 4 max
Standard Lasers	405, 488	405, 488, 561	405, 445, 488, 514, 561
Camera technology	EM-CCD	sCMOS	sCMOS
Objective lens	100x 1.4 NA	60x 1.42 NA	60x 1.42 NA
Imaging mode	Simultaneous or Sequential	Sequential (Simultaneous with additional cameras)	Simultaneous or Sequential
TIRF Illumination	Optional	Optional	Optional
Upgrade imaging mode	OMX Blaze upgrade optional	OMX Blaze upgrade optional	NA
Optional Accessories	DIC option, On stage sample heater. Piezo stage upgrade, optional lasers
* Additional cameras also require new filter configurations with are included in camera package

for more details see the following links:

http://www.api.com/whats-new.asp#omxv4

YouTube movie: http://www.youtube.com/watch?v=fNVF5TEW8dI&NR=1

http://www.youtube.com/watch?v=xQYwUI9Jy_0

http://cbst.ucdavis.edu/research/omx

OMX Labs

Click on the links below to view labs’ websites that are using DeltaVision OMX imaging systems:

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Applied Precision, LLC

Life Sciences

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